23A radical development for enzymatic fluorination

Gross, E.J.; Biegasiewicz, K.F.* Nat. Synth. 2024, https://doi.org/10.1038/s44160-024-00540-6

22Decarboxylative Halogenation of Indoles by Vanadium Haloperoxidases

Harstad, L.J.; Wells, C.E.; Lee, H.J.; Ramos, L.P.T.; Sharma, M.; Pascoe, C.A.; Biegasiewicz, K.F.*

Chem. Commun. 2023, 59, 14289.

Part of the 2023 Emerging Investigators Collection

21Chemoenzymatic Synthesis: Cooperativity Enables Opportunity

Hessefort, L.Z.; Harstad, L.J.; Merker, K.R.; Ramos, L.P.T.; Biegasiewicz, K.F.*

ChemBioChem 202324 (12), 1-17.

20Decarboxylative Bromooxidation of Indoles by a Vanadium Haloperoxidase

Wells, C.E.; Ramos, L.P.T.; Harstad, L.J.; Hessefort, L.Z.; Lee, H.J.; Sharma, M.;
Biegasiewicz, K.F.*

ACS Catal. 2023, 13 (7), 4622.

19A Radical-Relay Approach to Biocatalytic C-N Bond Formation

Tennant, J.J.; Biegasiewicz, K.F.*

Chem Catalysis 2022, 2, 2448.

18Quaternary Charge-Transfer Complex Enables Photoenzymatic Intermolecular Hydroalkylation of Olefins

Page, C.G.; Cooper, S.J.; DeHovitz, J.S.; Oblinsky, D.G.; Biegasiewicz, K.F.; Antropow, A.H.; Armbrust, K.W.; Ellis, J.M.; Harmann, L.G.; Horn, E.J.; Oberg, K.M.; Scholes, G.D.; Hyster, T.K.*

J. Am. Chem. Soc. 2021, 143 (1), 97.

17Organic Chemistry: A Retrosynthetic Approach to a Diverse Field

Ackerman-Biegasiewicz, L.K.G.; Arias-Rotondo, D.M.; Biegasiewicz, K.F.; Elacqua, E.*; Golder, M.R.; Kayser, L.V.; Lamb, J.R.; Le, C.M.; Romero, N.A.; Wilkerson-Hill, S.M.; Williams, D.A.

ACS Cent. Sci. 2020, 6 (11), 1845.

16Photoenzymatic Hydrogenation of Heteroaromatic Olefins Using ‘Ene’-Reductases with Photoredox Catalysts

Nakano, Y.; Black, M.J.; Meichan, A.J.; Sandoval, B.A.; Chung, M.M.; Biegasiewicz, K.F.; Zhu, T.; Hyster, T.K.*

Angew. Chem. Int. Ed. 202059 (26), 10484.

15Asymmetric Redox-Neutral Radical Cyclization Catalysed by Flavin-Dependent ‘Ene’-Reductases​

Black, M.J.; Biegasiewicz, K.F. Meichan, A.J.; Oblinsky, D.G.; Kudisch, B.; Scholes, G.D.; Hyster, T.K.*

Nat. Chem. 202012, 71.

14Photoenzymatic Catalysis Enables Radical‐Mediated Ketone Reduction in Ene‐Reductases

Sandoval, B.A.; Kurtoic, S.I.; Chung, M.M.; Biegasiewicz, K.F.; Hyster, T.K.*

Angew. Chem. Int. Ed. 2019, 58, 8714.

13Photoexcitation of Flavoenzymes Enables a Stereoselective Radical Cyclization

Biegasiewicz, K.F.; Cooper, S.J.; Gao, X.; Oblinsky, D.G.; Kim, J.H.; Garfinkle, S.E.; Joyce, L.A.; Sandoval, B.A.; Scholes, G.D.; Hyster T.K.*

Science 2019, 364, 1166.

12Biocatalytic Hydrogen Atom Transfer: an Invigorating Approach to Free-Radical Reactions

Nakano, Y.; Biegasiewicz, K.F.; Hyster, T.K.*

Curr. Opin. Chem. Biol. 2019, 49, 16-24.

11Catalytic Promiscuity Enabled by Photoredox Catalysis in Nicotinamide-Dependent Oxidoreductases

Biegasiewicz, K.F.; Cooper, S.J.; Emmanuel, M.A.; Miller, D.C.; Hyster, T.K.*

Nat. Chem. 2018, 10, 770.

10Scalable Synthesis of (−)-Rasfonin Enabled by a Convergent Enantioselective α-Hydroxymethylation Strategy

Boeckman Jr., R.K.*; Niziol, J.M.; Biegasiewicz, K.F.

Org. Lett. 2018, 20 (16), 5062.


Concepcion, A.B.; Yamamoto, H.; Boeckman Jr., R.K.; Biegasiewicz, K.F.; Tusch, D.J.

e-EROS Encyc. Reagents Org. Synth. 2018.

8Organocatalyzed Direct Asymmetric α-Hydroxymethylation of Aldehydes

Boeckman, Jr., R.K.*; Tusch, D.J.; Biegasiewicz, K.F.

Org. Synth. 2015, 92, 320.

7(S)-1,1-Diphenylprolinol Trimethylsilyl Ether

Boeckman, Jr., R.K.*; Tusch, D.J.; Biegasiewicz, K.F.

Org. Synth. 2015, 92, 309.

6Organocatalytic Enantioselective α-Hydroxymethylation of Aldehydes: Mechanistic Aspects and Optimization

Boeckman, Jr., R.K.*; Biegasiewicz, K.F.; Tusch, D.J.; Miller, J.R.

J. Org. Chem. 2015, 80 (8), 4030.

5Cubane: 50 Years Later

Biegasiewicz, K.F.; Griffiths, J.R.; Savage, G.P.; Tsanaktsidis, J.; Priefer, R.*

Chem. Rev. 2015, 115 (14), 6719.

4Development of a General Approach to the Synthesis of a Library of Isoflavonoid Derivatives

Biegasiewicz, K.F.; Gordon IV, J.S.; Rodriguez, D.A.; Priefer, R.*

Tetrahedron Lett. 2014, 55, 5210.

3CHAPTER 5. Chemistry and Synthesis of Daidzein and its Methylated Derivatives: Formononetin, Isoformononetin, and Dimethyldaidzein

Carroll, V.M.; St. Denis, J.D.; Biegasiewicz, K.F.; Priefer, R.*

Food Nutr. Compon. Focus 2013, 5 (isoflavones), 61.

2Evaluation of a Chiral Cubane-Based Schiff Base Ligand in Asymmetric Catalysis Reactions

Biegasiewicz, K.F.; Ingalsbe, M.L.; St. Denis, J.D.; Gleason, J.L.; Ho, J.; Coote, M.L.; Savage, G.P.; Priefer, R.*

Beilstein J. Org. Chem. 2012, 8, 1814.

1An Efficient Synthesis of Daidzein, Dimethyldaidzein, and Isoformononetin

Biegasiewicz, K.F.; St. Denis, J.D.; Carroll, V.M.; Priefer, R.*

Tetrahedron Lett. 2010, 51, 4408.